Symbol
Name
ID

Pbx1
pre B cell leukemia homeobox 1
MGI:97495

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal thymus morphology

small thymus

thymus hypoplasia

ectopic thymus

decreased pro-B cell number

decreased double-negative T cell number

decreased mature B cell number

decreased B cell number

decreased pre-B cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased T cell number

abnormal spleen morphology

abnormal spleen mesenchyme morphology

small spleen

spleen hypoplasia

absent spleen

abnormal lymph node primary follicle morphology

Availability

Mouse Genotype

Pbx1^em1Dunw/Pbx1^em1Dunw

Pbx1^tm1Mlc/Pbx1^tm1Mlc

Pbx1^tm1Mlc/Pbx1^tm2.1Mlc

Nkx2-5^tm2(cre)Rph/Nkx2-5⁺
Pbx1^tm1.1Koss/Pbx1^tm1.1Koss (conditional)

Pbx1^tm1.1Koss/Pbx1^tm1.1Koss
Tg(WT1-cre)AG11Dbdr/0 (conditional)

Pbx1^tm1Koss/Pbx1^tm1Koss
Nkx2-5^tm2(cre)Rph/Nkx2-5⁺ (conditional)

Pbx1^tm1.1Koss/Pbx1^tm1.2Koss
Tmem163^{Tg(ACTB-cre)2Mrt}/0 (conditional)

Pbx1^tm1Mlc/Pbx1^tm3.1Mlc
Tg(Tek-cre)1Ywa/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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