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Symbol
Name
ID

Lipa
lysosomal acid lipase A
MGI:96789

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Leukopenia	Bone-marrow foam cells	Splenomegaly	Hepatosplenomegaly	Hypersplenism
Disease(s) Associated with LIPA	Leukopenia	Bone-marrow foam cells	Splenomegaly	Hepatosplenomegaly	Hypersplenism
cholesterol ester storage disease
Wolman disease

Mouse Phenotypes		abnormal Kupffer cell morphology	hepatosplenomegaly	enlarged spleen	increased spleen weight	abnormal alveolar macrophage morphology	abnormal spleen morphology	enlarged mesenteric lymph nodes	chronic inflammation	liver inflammation	lung inflammation
Availability	Mouse Genotype	abnormal Kupffer cell morphology	hepatosplenomegaly	enlarged spleen	increased spleen weight	abnormal alveolar macrophage morphology	abnormal spleen morphology	enlarged mesenteric lymph nodes	chronic inflammation	liver inflammation	lung inflammation
	Lipa^tm1Ggb/Lipa^tm1Ggb
	Lipa^{tm1c(EUCOMM)Hmgu}/Lipa^{tm1c(EUCOMM)Hmgu} Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1^{Tg(Alb-cre)21Mgn} (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23