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Symbol Name ID |
Lgals3
lectin, galactose binding, soluble 3 MGI:96778 |
| Darker colors indicate more annotations |
| Human Phenotypes | Asthma |
| Disease(s) Associated with LGALS3 | |
| asthma |
| Mouse Phenotypes | increased macrophage apoptosis |
impaired macrophage chemotaxis |
impaired macrophage phagocytosis |
small intestinal inflammation |
peritoneal inflammation |
increased eosinophil cell number |
decreased granulocyte number |
decreased lymphocyte cell number |
decreased macrophage cell number |
decreased monocyte cell number |
abnormal CD8-positive, alpha-beta cytotoxic T cell morphology |
abnormal monocyte morphology |
abnormal leukocyte physiology |
impaired neutrophil recruitment |
increased IgG level |
abnormal macrophage physiology |
abnormal dendritic cell physiology |
abnormal interferon secretion |
increased interleukin-12b secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
brain inflammation |
liver inflammation |
lung inflammation |
abnormal response to infection |
increased susceptibility to bacterial infection |
increased susceptibility to parasitic infection |
sepsis |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Lgals3tm1Ftl/Lgals3tm1Ftl | |||||||||||||||||||||||||||||
| Lgals3tm1Poi/Lgals3tm1Poi | |||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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