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Symbol Name ID |
Itgav
integrin alpha V MGI:96608 |
| Darker colors indicate more annotations |
| Human Phenotypes | Acute myeloid leukemia |
| Disease(s) Associated with ITGAV | |
| acute myeloid leukemia |
| Mouse Phenotypes | abnormal dendritic cell differentiation |
impaired macrophage phagocytosis |
large intestinal inflammation |
colitis |
decreased regulatory T cell number |
increased regulatory T cell number |
abnormal leukocyte morphology |
abnormal interferon level |
abnormal interleukin level |
abnormal tumor necrosis factor level |
abnormal immune system morphology |
enlarged Peyer's patches |
enlarged mesenteric lymph nodes |
abnormal immune system physiology |
increased autoantibody level |
increased inflammatory response |
increased susceptibility to bacterial infection induced morbidity/mortality |
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| Availability | Mouse Genotype | |||||||||||||||||
| Itgavtm2Hyn/Itgavtm2.1Hyn Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Itgavtm2Hyn/Itgavtm2.1Hyn Tg(Tek-cre)1Ywa/? (conditional) |
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| Itgavtm2Hyn/Itgavtm2.1Hyn Tg(Nes-cre)1Kln/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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