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Symbol
Name
ID

Grn
granulin
MGI:95832

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

microgliosis

abnormal macrophage physiology

abnormal microglial cell physiology

abnormal chemokine secretion

increased interleukin-1 beta secretion

increased interleukin-10 secretion

increased interleukin-12 secretion

increased interleukin-6 secretion

increased tumor necrosis factor secretion

kidney inflammation

increased susceptibility to bacterial infection

Availability

Mouse Genotype

Grn^tm1.1Aidi/Grn^tm1.1Aidi

Grn^tm1.1Far/Grn^tm1.1Far

Grn^tm1.1Geno/Grn^tm1.1Geno

Grn^tm1Blrl/Grn^tm1Blrl

Grn^tm2.1Far/Grn^tm2.1Far

Grn^tm1Far/Grn^tm1Far
Tg(ITGAM-cre)2781Gkl/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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