Symbol Name ID |
Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2 MGI:95413 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA level |
Decreased circulating IgG level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Leukocytosis |
Abnormal granulocyte morphology |
Abnormal basophil morphology |
Acute lymphoblastic leukemia |
Ph-positive acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Chronic myelogenous leukemia |
Myeloproliferative disorder |
Conjunctivitis |
Keratoconjunctivitis sicca |
Blepharitis |
Lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Peritoneal abscess |
Subacute progressive viral hepatitis |
Keratitis |
Erythroderma |
Asthma |
Recurrent infections |
Disease(s) Associated with ERCC2 | ||||||||||||||||||||||||||
acute lymphoblastic leukemia | ||||||||||||||||||||||||||
acute myeloid leukemia | ||||||||||||||||||||||||||
chronic myeloid leukemia | ||||||||||||||||||||||||||
hepatocellular carcinoma | ||||||||||||||||||||||||||
multiple myeloma | ||||||||||||||||||||||||||
pancreatic cancer | ||||||||||||||||||||||||||
photosensitive trichothiodystrophy 1 | ||||||||||||||||||||||||||
xeroderma pigmentosum | ||||||||||||||||||||||||||
xeroderma pigmentosum group D |
Mouse Phenotypes | immune system phenotype |
enlarged spleen |
microgliosis |
|
Availability | Mouse Genotype | |||
Ercc2tm2(ERCC2)Jhjh/Ercc2tm2(ERCC2)Jhjh | * | |||
Ercc2tm3Jhjh/Ercc2tm3Jhjh |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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