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Symbol
Name
ID
Spib
Spi-B transcription factor (Spi-1/PU.1 related)
MGI:892986
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
increased B cell apoptosis
decreased B cell proliferation
abnormal immature B cell morphology
abnormal spleen white pulp morphology
abnormal spleen B cell follicle morphology
abnormal spleen germinal center morphology
decreased IgG1 level
decreased IgG2a level
decreased IgG2b level
increased IgM level
abnormal Peyer's patch morphology
abnormal humoral immune response
increased susceptibility to bacterial infection
Availability Mouse Genotype
Spibtm1Ksho/Spibtm1Ksho
Spibtm1Mcs/Spibtm1Mcs

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory