|
Symbol Name ID |
Cfh
complement component factor h MGI:88385 |
| Darker colors indicate more annotations |
| Human Phenotypes | Eosinophilia |
Increased T cell count |
Leukopenia |
Keratoconjunctivitis sicca |
Pericarditis |
Abnormal lymph node morphology |
Lymphadenopathy |
Uveitis |
Lupus nephritis |
Nephritis |
Abnormality of the immune system |
Erythema nodosum |
Discoid lupus rash |
Maculopapular exanthema |
Malar rash |
Serositis |
Decreased circulating complement C3 concentration |
Decreased circulating complement C4 concentration |
Antineutrophil antibody positivity |
Perinuclear antineutrophil antibody positivity |
Antinuclear antibody positivity |
Anti-dsDNA antibody positivity |
Anti-La/SS-B antibody positivity |
Anti-Sm antibody positivity |
Anti-U1 ribonucleoprotein antibody positivity |
Antiphospholipid antibody positivity |
Systemic lupus erythematosus |
| Disease(s) Associated with CFH | |||||||||||||||||||||||||||
| sarcoidosis | |||||||||||||||||||||||||||
| systemic lupus erythematosus |
| Mouse Phenotypes | abnormal circulating complement protein level |
decreased circulating complement protein level |
abnormal complement protein level |
decreased complement C5 level |
increased susceptibility to type III hypersensitivity reaction |
decreased serum complement activity |
glomerulonephritis |
|
| Availability | Mouse Genotype | |||||||
| Cfhtm1.1Song/Cfhtm1.1Song | ||||||||
| Cfhtm1Mbo/Cfhtm1Mbo | ||||||||
| Cfhtm1Mbo/Cfhtm1Mbo Tg(CAG-Cfh*)#Mcp/0 |
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| Cfhtm1Mbo/Cfh+ | ||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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