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Symbol
Name
ID

Cd3g
CD3 antigen, gamma polypeptide
MGI:88333

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Chronic decreased circulating IgG2	Autoimmune hemolytic anemia	Decreased proportion of CD8-positive T cells	T lymphocytopenia	Abnormal B cell morphology	Recurrent gastroenteritis	Recurrent otitis media	Eczematoid dermatitis	Chronic oral candidiasis	Immunodeficiency	Recurrent respiratory infections
Disease(s) Associated with CD3G
immunodeficiency 17

Mouse Phenotypes

immune system phenotype

increased T cell apoptosis

abnormal T cell proliferation

thymus hypoplasia

decreased thymocyte number

abnormal T cell differentiation

decreased CD8-positive, alpha-beta T cell number

spleen hypoplasia

abnormal T cell physiology

abnormal CD8-positive, alpha-beta T cell physiology

decreased cytotoxic T cell cytolysis

abnormal T cell activation

lymph node hypoplasia

abnormal response to infection

Availability

Mouse Genotype

Cd3g^tm1.1Cage/Cd3g^tm1.1Cage

Cd3g^tm1Amk/Cd3g^tm1Amk

Cd3g^tm2Amk/Cd3g^tm2Amk

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Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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