Symbol Name ID |
Braf
Braf transforming gene MGI:88190 |
Darker colors indicate more annotations |
Human Phenotypes | Lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Peritoneal abscess |
Atopic dermatitis |
Disease(s) Associated with BRAF | |||||
cardiofaciocutaneous syndrome 1 | |||||
pancreatic cancer |
Mouse Phenotypes | increased thymocyte apoptosis |
increased splenocyte apoptosis |
abnormal thymus morphology |
decreased thymus weight |
thymus atrophy |
decreased thymocyte number |
hepatosplenomegaly |
enlarged spleen |
increased spleen weight |
increased dendritic cell number |
decreased leukocyte cell number |
decreased spleen weight |
abnormal lymph organ development |
enlarged lymph nodes |
lymphoid hyperplasia |
abnormal immune system physiology |
cytokine storm |
granulomatous inflammation |
increased inflammatory response |
liver inflammation |
lung inflammation |
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Availability | Mouse Genotype | |||||||||||||||||||||
Braftm1(ARAF)Urr/Braftm1(ARAF)Urr | ||||||||||||||||||||||
Braftm1Bbd/Braf+ | ||||||||||||||||||||||
Braftm1Mmcm/Braftm1Mmcm Cd207tm2.1(cre)Bjec/Cd207+ (conditional) |
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Braftm1Mmcm/Braftm1Mmcm Tg(Itgax-cre)1-1Reiz/0 (conditional) |
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Braftm1Cpri/Braf+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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Braftm1Tumg/Braf+ Tg(CAG-cre)2Osb/0 (conditional) |
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Braftm2Cpri/Braf+ Tg(CMV-cre)1Cgn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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