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Symbol
Name
ID
Hdac4
histone deacetylase 4
MGI:3036234
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating IgA level
Decreased circulating IgG level
Decreased circulating IgG2 level
Defective B cell differentiation
Abnormal B cell count
Decreased proportion of CD4-positive helper T cells
T lymphocytopenia
Lymphopenia
Leukemia
Acute lymphoblastic leukemia
Sinusitis
Hypoplasia of the thymus
Recurrent lower respiratory tract infections
Recurrent bronchitis
Disease(s) Associated with HDAC4
ataxia telangiectasia

Mouse Phenotypes
increased NK cell number
Availability Mouse Genotype
Hdac4em1(IMPC)Ccpcz/Hdac4+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory