Symbol
Name
ID

Klhl6
kelch-like 6
MGI:2686922

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal thymus morphology

enlarged thymus

abnormal B cell differentiation

increased immature B cell number

decreased eosinophil cell number

decreased mature B cell number

decreased follicular B cell number

increased B-1 B cell number

increased B-1a cell number

increased B-1b cell number

decreased B cell number

decreased central memory CD4-positive, alpha-beta T cell number

increased CD4-positive, alpha-beta T cell number

decreased effector memory CD8-positive, alpha-beta T cell number

increased CD8-positive, naive alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

increased alpha-beta T cell number

decreased effector memory T-helper cell number

increased T-helper cell number

increased T cell number

increased single-positive T cell number

abnormal spleen morphology

decreased spleen weight

small spleen

spleen hypoplasia

abnormal lymph node germinal center morphology

abnormal adaptive immunity

Availability

Mouse Genotype

Klhl6^{em1(IMPC)Ccpcz}/Klhl6^{em1(IMPC)Ccpcz}

Klhl6^m1Anu/Klhl6^m1Anu

Klhl6^m1Btlr/Klhl6^m1Btlr

Klhl6^m2Btlr/Klhl6^m2Btlr

Klhl6^M3Btlr/Klhl6^M3Btlr

Klhl6^m4Btlr/Klhl6^m4Btlr

Klhl6^M5Btlr/Klhl6^M5Btlr

Klhl6^m6Btlr/Klhl6^m6Btlr

Klhl6^M7Btlr/Klhl6^M7Btlr

Klhl6^M8Btlr/Klhl6^M8Btlr

Klhl6^tm1Sato/Klhl6^tm1Sato

Cd19^tm1(cre)Cgn/Cd19⁺
Klhl6^tm2Sato/Klhl6^tm2Sato (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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