Symbol Name ID |
Cgas
cyclic GMP-AMP synthase MGI:2442261 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
abnormal macrophage physiology |
decreased circulating interferon-alpha level |
decreased circulating interferon-beta level |
abnormal dendritic cell physiology |
abnormal plasmacytoid dendritic cell physiology |
abnormal immune cell physiology |
abnormal interferon secretion |
increased susceptibility to Herpesvirales infection induced morbidity/mortality |
increased susceptibility to Poxviridae infection induced morbidity/mortality |
increased susceptibility to Flaviviridae infection induced morbidity/mortality |
increased susceptibility to Herpesvirales infection |
increased susceptibility to Retroviridae infection |
increased susceptibility to Poxviridae infection |
increased susceptibility to Flaviviridae infection |
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Availability | Mouse Genotype | |||||||||||||||
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu | ||||||||||||||||
Cgastm1d(EUCOMM)Hmgu/Cgastm1d(EUCOMM)Hmgu | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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