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Symbol
Name
ID

Dusp4
dual specificity phosphatase 4
MGI:2442191

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

immune system phenotype

decreased B cell apoptosis

increased T cell proliferation

increased CD4-positive, alpha-beta T cell number

increased IgG1 level

decreased IgG2a level

abnormal macrophage physiology

decreased interferon-gamma secretion

decreased interleukin-10 secretion

increased interleukin-10 secretion

increased interleukin-12 secretion

increased interleukin-13 secretion

increased interleukin-4 secretion

increased interleukin-6 secretion

increased tumor necrosis factor secretion

increased susceptibility to parasitic infection

Availability

Mouse Genotype

Dusp4^Gt(XG164)Byg/Dusp4^Gt(XG164)Byg

*

Dusp4^tm1Jmol/Dusp4^tm1Jmol

Dusp4^tm1Plev/Dusp4^tm1Plev

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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