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Symbol Name ID |
Map4k3
mitogen-activated protein kinase kinase kinase kinase 3 MGI:2154405 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
decreased T cell proliferation |
abnormal T-helper 1 cell differentiation |
abnormal T-helper 2 cell differentiation |
abnormal T-helper 17 cell differentiation |
decreased IgG1 level |
decreased IgG2a level |
decreased IgG2b level |
decreased IgG3 level |
decreased IgM level |
decreased immunoglobulin level |
decreased interferon-gamma secretion |
abnormal interleukin secretion |
decreased interleukin-17 secretion |
decreased interleukin-2 secretion |
decreased interleukin-4 secretion |
decreased susceptibility to experimental autoimmune encephalomyelitis |
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| Availability | Mouse Genotype | |||||||||||||||||
| Map4k3Gt(RRO270)Byg/Map4k3Gt(RRO270)Byg | * | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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