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Symbol
Name
ID

Lrba
LPS-responsive beige-like anchor
MGI:1933162

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes

Decreased circulating IgA concentration

Decreased circulating IgG concentration

Decreased circulating total IgM

Decreased specific antibody response to vaccination

Autoimmune hemolytic anemia

Persistently decreased total neutrophil count

Decreased class-switched memory B cell proportion

Decreased total B cell count

Autoimmune thrombocytopenia

Recurrent sinusitis

Conjunctivitis

Lymphadenopathy

Generalized lymphadenopathy

Splenomegaly

Inflammation of the large intestine

Colitis

Recurrent otitis media

Thyroiditis

Uveitis

Erythema nodosum

Pneumonia

Recurrent pneumonia

Immunodeficiency

Asthma

Sepsis

Recurrent infections

Recurrent respiratory infections

Disease(s) Associated with LRBA

common variable immunodeficiency 8

Mouse Phenotypes		increased susceptibility to induced colitis	increased regulatory T cell number	abnormal NK cell physiology	impaired natural killer cell mediated cytotoxicity	decreased susceptibility to graft versus host disease	increased length of allograft survival
Availability	Mouse Genotype	increased susceptibility to induced colitis	increased regulatory T cell number	abnormal NK cell physiology	impaired natural killer cell mediated cytotoxicity	decreased susceptibility to graft versus host disease	increased length of allograft survival
	Lrba^em1Btlr/Lrba^em1Btlr
	Lrba^em2Btlr/Lrba^em2Btlr
	Lrba^em3Btlr/Lrba^em3Btlr
	Lrba^{Gt(OST69142)Lex}/Lrba^{Gt(OST69142)Lex}
	Lrba^m1Btlr/Lrba^m1Btlr
	Lrba^m2Btlr/Lrba^m2Btlr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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