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Symbol
Name
ID
Il23a
interleukin 23, alpha subunit p19
MGI:1932410
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
decreased T cell proliferation
decreased susceptibility to induced colitis
increased susceptibility to induced colitis
decreased neutrophil cell number
decreased gamma-delta T cell number
decreased T cell number
decreased activated T cell number
decreased leukocyte cell number
abnormal CD8-positive, alpha beta T cell morphology
abnormal granulocyte physiology
decreased IgA level
decreased IgG2a level
decreased immunoglobulin level
abnormal CD4-positive, alpha-beta T cell physiology
abnormal CD8-positive, alpha-beta T cell physiology
abnormal memory T cell physiology
abnormal macrophage physiology
abnormal circulating interleukin level
increased circulating interleukin-17 level
abnormal interleukin level
decreased interferon-gamma secretion
decreased interleukin-17 secretion
decreased susceptibility to experimental autoimmune encephalomyelitis
granulomatous inflammation
increased susceptibility to bacterial infection
increased susceptibility to bacterial infection induced morbidity/mortality
Availability Mouse Genotype
Il23atm1.1Thak/Il23atm1.1Thak
Il23atm1Dnax/Il23atm1Dnax
Il23atm1Gdy/Il23atm1Gdy
Il23atm1Ngh/Il23atm1Ngh
Il23atm1Gdy/Il23a+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory