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Symbol Name ID |
Pycard
PYD and CARD domain containing MGI:1931465 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | increased susceptibility to induced colitis |
decreased NK cell number |
increased IgA level |
increased IgG2c level |
abnormal macrophage physiology |
decreased circulating interleukin-1 beta level |
decreased circulating interleukin-18 level |
enlarged Peyer's patches |
decreased susceptibility to type IV hypersensitivity reaction |
increased interferon-beta secretion |
decreased interferon-gamma secretion |
decreased interleukin-1 alpha secretion |
decreased interleukin-1 beta secretion |
decreased interleukin-18 secretion |
decreased interleukin-6 secretion |
decreased tumor necrosis factor secretion |
increased tumor necrosis factor secretion |
decreased susceptibility to endotoxin shock |
decreased inflammatory response |
abnormal response to infection |
increased susceptibility to Herpesvirales infection |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Pycardtm1Flv/Pycardtm1Flv | ||||||||||||||||||||||
| Pycardtm1Nnz/Pycardtm1Nnz | ||||||||||||||||||||||
| Pycardtm1Tno/Pycardtm1Tno | ||||||||||||||||||||||
| Pycardtm1Vmd/Pycardtm1Vmd | ||||||||||||||||||||||
| Pycardtm1Ayaz/Pycardtm1Ayaz Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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