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Symbol Name ID |
Irak3
interleukin-1 receptor-associated kinase 3 MGI:1921164 |
| Darker colors indicate more annotations |
| Human Phenotypes | Asthma |
| Disease(s) Associated with IRAK3 | |
| asthma |
| Mouse Phenotypes | insulitis |
abnormal T cell differentiation |
increased neutrophil cell number |
increased effector memory T-helper cell number |
increased osteoclast cell number |
abnormal T cell activation |
abnormal osteoclast physiology |
abnormal immune system morphology |
abnormal Peyer's patch morphology |
enlarged Peyer's patches |
abnormal professional antigen presenting cell physiology |
abnormal dendritic cell physiology |
increased interleukin-12b secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
increased susceptibility to autoimmune diabetes |
increased anti-insulin autoantibody level |
abnormal inflammatory response |
increased susceptibility to endotoxin shock |
abnormal innate immunity |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Irak3tm1Flv/Irak3tm1Flv | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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