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Symbol Name ID |
Phf6
PHD finger protein 6 MGI:1918248 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Acute myeloid leukemia |
| Disease(s) Associated with PHF6 | |
| acute myeloid leukemia |
| Mouse Phenotypes | immune system phenotype |
abnormal thymus cell ratio |
decreased DN2 thymocyte number |
enlarged spleen |
increased pro-B cell number |
abnormal T cell differentiation |
decreased double-negative T cell number |
increased plasmacytoid dendritic cell number |
increased B cell number |
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
abnormal effector T cell number |
decreased lymphocyte cell number |
increased leukocyte cell number |
abnormal splenic cell ratio |
increased circulating interferon-alpha level |
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| Availability | Mouse Genotype | |||||||||||||||||
| Phf6em1Wencc/Phf6em1Wencc Tg(Vav1-cre)#Cgp/0 (conditional) |
* | |||||||||||||||||
| Phf6em1Wencc/Y Tg(Vav1-cre)#Cgp/0 (conditional) |
* | |||||||||||||||||
| Phf6tm1.1Avo/Y Tg(Tek-cre)1Ywa/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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