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Symbol Name ID |
Unc13d
unc-13 homolog D MGI:1917700 |
| Darker colors indicate more annotations |
| Human Phenotypes | Reduced natural killer cell activity |
Granulocytopenia |
Hemophagocytosis |
Hepatosplenomegaly |
| Disease(s) Associated with UNC13D | ||||
| familial hemophagocytic lymphohistiocytosis 3 |
| Mouse Phenotypes | enlarged spleen |
increased neutrophil cell number |
increased CD8-positive, alpha-beta T cell number |
increased monocyte cell number |
abnormal NK cell physiology |
decreased cytotoxic T cell cytolysis |
abnormal macrophage physiology |
hemophagocytosis |
absent lymph node germinal center |
abnormal cytokine secretion |
increased susceptibility to Herpesvirales infection |
increased susceptibility to Riboviria infection |
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| Availability | Mouse Genotype | ||||||||||||
| Unc13dJinx/Unc13dJinx | |||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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