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Symbol
Name
ID
Foxp1
forkhead box P1
MGI:1914004
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Recurrent upper respiratory tract infections
Recurrent otitis media
Recurrent skin infections
Allergy
Disease(s) Associated with FOXP1
intellectual disability-severe speech delay-mild dysmorphism syndrome

Mouse Phenotypes
immune system phenotype
increased T cell apoptosis
abnormal B cell differentiation
arrested B cell differentiation
decreased mature B cell number
decreased CD4-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
abnormal B cell physiology
abnormal T cell activation
Availability Mouse Genotype
Foxp1tm1Rao/Foxp1tm1Rao
Foxp1tm1.1Pwt/Foxp1tm1.1Pwt
Tg(Cd4-cre)1Cwi/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory