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Symbol Name ID |
Becn1
beclin 1, autophagy related MGI:1891828 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | increased T cell apoptosis |
decreased T cell proliferation |
increased neutrophil cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased lymphocyte cell number |
increased monocyte cell number |
increased leukocyte cell number |
abnormal spleen morphology |
increased spleen germinal center number |
increased spleen germinal center size |
increased IgG level |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal macrophage physiology |
abnormal circulating chemokine level |
increased circulating interleukin-1 beta level |
decreased circulating interleukin-10 level |
increased circulating interleukin-12b level |
increased circulating interleukin-6 level |
abnormal immune system morphology |
decreased susceptibility to experimental autoimmune encephalomyelitis |
increased susceptibility to systemic lupus erythematosus |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
glomerulonephritis |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Becn1tm1b(KOMP)Wtsi/Becn1+ | |||||||||||||||||||||||||||
| Becn1tm1Blev/Becn1+ | |||||||||||||||||||||||||||
| Becn1tm1.1Bflu/Becn1tm1.1Bflu Tg(Cd4-cre)1Cwi/0 (conditional) |
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| Becn1tm1Ebr/Becn1tm1Ebr Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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