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Symbol
Name
ID
Mefv
Mediterranean fever
MGI:1859396
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Neutrophilia
Leukocytosis
Acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemias
Acute myeloid leukemia
Pericarditis
Lymphadenopathy
Splenomegaly
Crohn's disease
Peritonitis
Pancreatitis
Erysipelas
Skin rash
Asthma
Meningitis
Disease(s) Associated with MEFV
acute lymphoblastic leukemia
acute myeloid leukemia
asthma
familial Mediterranean fever
multiple myeloma

Mouse Phenotypes
immune system phenotype
decreased macrophage apoptosis
increased interleukin-1 beta secretion
increased interleukin-18 secretion
increased susceptibility to endotoxin shock
increased inflammatory response
Availability Mouse Genotype
Mefvtm1Bhk/Mefvtm1Bhk *
Mefvtm1Chae/Mefvtm1Chae

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory