Symbol
Name
ID

Nfat5
nuclear factor of activated T cells 5
MGI:1859333

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

decreased T cell proliferation

decreased splenocyte proliferation

thymus hypoplasia

abnormal T cell differentiation

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased T cell number

spleen hypoplasia

abnormal immunoglobulin level

decreased IgG level

abnormal T cell physiology

abnormal cytotoxic T cell physiology

abnormal lymphatic vessel morphology

tubulointerstitial nephritis

Availability

Mouse Genotype

Nfat5^tm1Rao/Nfat5^tm1Rao

Nfat5^tm1Snh/Nfat5⁺

Tg(CD2-Nfat5)1Snh/0

Nfat5^tm1.1Itl/Nfat5^tm1.1Itl
Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Nfat5^tm1.1Joar/Nfat5^tm1.1Joar
Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 06/04/2024 MGI 6.13