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Symbol
Name
ID

Irf7
interferon regulatory factor 7
MGI:1859212

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Immunodeficiency	Severe influenza infection
Disease(s) Associated with IRF7	Immunodeficiency	Severe influenza infection
immunodeficiency 39

Mouse Phenotypes		abnormal T cell physiology	decreased circulating interferon-beta level	abnormal interferon level	decreased interferon-alpha secretion	decreased interferon-beta secretion	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	increased susceptibility to Herpesvirales infection	increased susceptibility to Orthomyxoviridae infection	increased susceptibility to Picornaviridae infection
Availability	Mouse Genotype	abnormal T cell physiology	decreased circulating interferon-beta level	abnormal interferon level	decreased interferon-alpha secretion	decreased interferon-beta secretion		increased susceptibility to Herpesvirales infection	increased susceptibility to Orthomyxoviridae infection	increased susceptibility to Picornaviridae infection
	Irf7^m1Btlr/Irf7^m1Btlr
	Irf7^M2Btlr/Irf7^M2Btlr
	Irf7^tm1Ttg/Irf7^tm1Ttg
	Irf7^m1Btlr/Irf7⁺
	Irf7^M2Btlr/Irf7⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/28/2024 MGI 6.13