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Symbol
Name
ID

Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
MGI:1344376

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

decreased T cell proliferation

salivary gland inflammation

enlarged spleen

abnormal B cell differentiation

decreased transitional stage B cell number

increased immature B cell number

increased transitional stage B cell number

increased transitional stage T2 B cell number

arrested B cell differentiation

decreased mature B cell number

decreased follicular B cell number

decreased marginal zone B cell number

increased mature B cell number

increased B-1a cell number

increased B-1b cell number

increased marginal zone B cell number

increased plasma cell number

decreased B cell number

increased B cell number

abnormal T cell subpopulation ratio

abnormal T cell number

decreased memory T cell number

increased T cell number

increased single-positive T cell number

increased lymphocyte cell number

abnormal leukocyte morphology

abnormal lymphocyte morphology

abnormal B cell morphology

abnormal B-1 B cell morphology

abnormal spleen morphology

decreased spleen weight

spleen hypoplasia

increased spleen B cell follicle size

abnormal spleen follicular dendritic cell network

abnormal spleen germinal center morphology

increased spleen germinal center size

abnormal spleen marginal zone morphology

abnormal spleen periarteriolar lymphoid sheath morphology

abnormal B cell physiology

abnormal B cell activation

abnormal immunoglobulin level

increased IgA level

decreased IgG level

increased IgG level

decreased IgM level

increased IgM level

decreased immunoglobulin level

increased immunoglobulin level

abnormal marginal zone B cell physiology

abnormal T cell physiology

enlarged Peyer's patches

abnormal lymph node B cell domain morphology

enlarged lymph nodes

lymph node hypoplasia

abnormal lymph organ size

abnormal humoral immune response

impaired humoral immune response

increased autoantibody level

increased anti-double stranded DNA antibody level

increased anti-single stranded DNA antibody level

kidney inflammation

glomerulonephritis

increased length of allograft survival

Availability

Mouse Genotype

Tg(Tnfsf13b)1Fma/Tg(Tnfsf13b)1Fma

Tnfsf13b^m1Anu/Tnfsf13b^m1Anu

Tnfsf13b^M1Btlr/Tnfsf13b^M1Btlr

Tnfsf13b^m2Btlr/Tnfsf13b^m2Btlr

Tnfsf13b^m3Btlr/Tnfsf13b^m3Btlr

Tnfsf13b^tm1Cleg/Tnfsf13b^tm1Cleg

Tnfsf13b^tm1Msc/Tnfsf13b^tm1Msc

Tnfsf13b^M1Btlr/Tnfsf13b⁺

Tnfsf13b^tm1Msc/Tnfsf13b⁺

Tg(Tnfsf13b)1Fma/0

Tg(Tnfsf13b)1Fma/?

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23