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Symbol Name ID |
Parp1
poly (ADP-ribose) polymerase family, member 1 MGI:1340806 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Autoimmunity |
Autoimmune antibody positivity |
Asthma |
| Disease(s) Associated with PARP1 | |||
| asthma | |||
| autoimmune disease |
| Mouse Phenotypes | immune system phenotype |
abnormal leukocyte migration |
enlarged spleen |
decreased NK cell number |
increased effector memory CD8-positive, alpha-beta T cell number |
abnormal spleen morphology |
abnormal macrophage physiology |
abnormal microglial cell physiology |
decreased circulating interleukin-1 beta level |
decreased circulating tumor necrosis factor level |
abnormal inflammatory response |
decreased susceptibility to endotoxin shock |
decreased inflammatory response |
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| Availability | Mouse Genotype | |||||||||||||
| Parp1em1(IMPC)Ccpcz/Parp1em1(IMPC)Ccpcz | ||||||||||||||
| Parp1tm1b(EUCOMM)Hmgu/Parp1tm1b(EUCOMM)Hmgu | ||||||||||||||
| Parp1tm1Jmdm/Parp1tm1Jmdm | * | |||||||||||||
| Parp1tm1Zqw/Parp1tm1Zqw | * | |||||||||||||
| Parp1tm2Zqw/Parp1tm2Zqw | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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