Symbol
Name
ID

Cflar
CASP8 and FADD-like apoptosis regulator
MGI:1336166

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

increased thymocyte apoptosis

abnormal thymus morphology

abnormal thymus corticomedullary boundary morphology

enlarged spleen

abnormal myelopoiesis

increased eosinophil cell number

increased neutrophil cell number

increased granulocyte number

abnormal lymphocyte cell number

abnormal B cell number

abnormal CD4-positive, alpha-beta T cell number

abnormal CD8-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased single-positive T cell number

decreased macrophage cell number

increased monocyte cell number

increased leukocyte cell number

abnormal spleen morphology

abnormal spleen red pulp morphology

abnormal spleen B cell follicle morphology

abnormal spleen marginal zone morphology

abnormal abdominal lymph node morphology

Availability

Mouse Genotype

Cflar^tm1Ywh/Cflar^tm1Ywh
Tg(Lck-cre)548Jxm/0 (conditional)

Cflar^tm1.1Pope/Cflar^tm1.2Pope
Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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