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Symbol Name ID |
Atg5
autophagy related 5 MGI:1277186 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | decreased T cell proliferation |
abnormal thymus cortex morphology |
increased neutrophil cell number |
abnormal T cell subpopulation ratio |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased T cell number |
increased lymphocyte cell number |
increased monocyte cell number |
abnormal T cell morphology |
increased IgG level |
abnormal T cell physiology |
abnormal macrophage physiology |
abnormal circulating chemokine level |
increased circulating interleukin-1 beta level |
decreased circulating interleukin-10 level |
increased circulating interleukin-12b level |
increased circulating interleukin-6 level |
increased susceptibility to systemic lupus erythematosus |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
glomerulonephritis |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Atg5tm1Nmz/Atg5tm1Nmz | ||||||||||||||||||||||||
| Atg5tm1Myok/Atg5tm1Myok Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Atg5tm1Nmz/Atg5tm1Nmz Tg(Cd4-cre)1Cwi/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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