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Symbol
Name
ID

Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
MGI:1206581

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Splenomegaly	Subacute progressive viral hepatitis	Thyroiditis
Disease(s) Associated with PIK3CA	Splenomegaly	Subacute progressive viral hepatitis	Thyroiditis
CLOVES syndrome
Cowden syndrome 5
hepatocellular carcinoma

Mouse Phenotypes		abnormal spleen morphology	abnormal lymphatic vessel morphology	abnormal lymphangiogenesis	enlarged lymphatic vessel
Availability	Mouse Genotype	abnormal spleen morphology	abnormal lymphatic vessel morphology	abnormal lymphangiogenesis	enlarged lymphatic vessel
	Pik3ca^tm1Jdo/Pik3ca^tm1Jdo
	Gt(ROSA)26Sor^{tm7(Pik3ca,EGFP)Rsky}/Gt(ROSA)26Sor⁺ Tg(CAG-cre/Esr1)5Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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