Symbol Name ID |
Pkn1
protein kinase N1 MGI:108022 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
decreased activation-induced B cell apoptosis |
increased B cell proliferation |
abnormal somatic hypermutation frequency |
decreased neutrophil cell number |
increased germinal center B cell number |
decreased lymphocyte cell number |
decreased large unstained cell number |
decreased monocyte cell number |
decreased leukocyte cell number |
increased spleen germinal center size |
increased splenocyte number |
abnormal germinal center B cell physiology |
increased IgG1 level |
increased IgG2a level |
increased IgG2b level |
increased IgM level |
increased anti-double stranded DNA antibody level |
glomerulonephritis |
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Availability | Mouse Genotype | |||||||||||||||||||
Pkn1tm1b(KOMP)Wtsi/Pkn1tm1b(KOMP)Wtsi | ||||||||||||||||||||
Pkn1tm1Kik/Pkn1tm1Kik | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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