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Symbol Name ID |
Bcl6
B cell leukemia/lymphoma 6 MGI:107187 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
white adipose tissue inflammation |
heart inflammation |
myocarditis |
decreased B cell proliferation |
small thymus |
spleen hyperplasia |
abnormal somatic hypermutation frequency |
abnormal T follicular helper cell differentiation |
increased eosinophil cell number |
decreased germinal center B cell number |
absent germinal center B cells |
decreased T follicular helper cell number |
abnormal memory B cell morphology |
abnormal spleen morphology |
spleen hypoplasia |
absent spleen germinal center |
abnormal B cell physiology |
decreased IgG level |
decreased IgM level |
abnormal memory B cell physiology |
abnormal T-helper 2 physiology |
abnormal chemokine level |
abnormal immune system morphology |
abnormal Peyer's patch morphology |
abnormal Peyer's patch germinal center morphology |
absent lymph node germinal center |
abnormal immune system physiology |
abnormal humoral immune response |
increased interleukin-10 secretion |
decreased interleukin-4 secretion |
increased inflammatory response |
liver inflammation |
lung inflammation |
increased susceptibility to bacterial infection |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
| Bcl6tm1.1Toka/Bcl6tm1.1Toka | * | |||||||||||||||||||||||||||||||||||
| Bcl6tm1Htno/Bcl6tm1Htno | ||||||||||||||||||||||||||||||||||||
| Bcl6tm1Rdf/Bcl6tm1Rdf | ||||||||||||||||||||||||||||||||||||
| Bcl6tm1Sdt/Bcl6tm1Sdt | ||||||||||||||||||||||||||||||||||||
| Bcl6tm2Rdf/Bcl6tm2Rdf | ||||||||||||||||||||||||||||||||||||
| Bcl6tm1.1Dent/Bcl6tm1.1Dent Tg(Cd4-cre)1Cwi/0 (conditional) |
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| Bcl6tm1.1Mtto/Bcl6tm1.1Mtto Cd79atm1(cre)Reth/Cd79a+ (conditional) |
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| Bcl6tm1.1Mtto/Bcl6tm1.1Mtto Ighg1tm1(cre)Cgn/Ighg1+ (conditional) |
* | |||||||||||||||||||||||||||||||||||
| Bcl6tm1.1Mtto/Bcl6tm1.1Mtto Tg(Cd4-cre)1Cwi/0 (conditional) |
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| Bcl6tm1.1Mtto/Bcl6tm1.1Mtto Cd79atm1(cre)Reth/Cd79a+ Tg(Cd4-cre)1Cwi/0 (conditional) |
* | |||||||||||||||||||||||||||||||||||
| Bcl6tm1Gdba/Bcl6tm1Gdba Tg(Adipoq-cre)1Evdr/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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