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Symbol
Name
ID
Zranb1
zinc finger, RAN-binding domain containing 1
MGI:106441
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
increased susceptibility to colitis induced morbidity/mortality
decreased T helper 1 cell number
decreased T-helper 17 cell number
decreased CD4-positive, alpha-beta T cell number
decreased circulating interferon-gamma level
decreased circulating interleukin-17 level
abnormal dendritic cell physiology
decreased susceptibility to experimental autoimmune encephalomyelitis
Availability Mouse Genotype
Zranb1em1Shios/Zranb1em1Shios
Zranb1tm1d(EUCOMM)Hmgu/Zranb1tm1d(EUCOMM)Hmgu *
Zranb1tm1c(EUCOMM)Hmgu/Zranb1tm1c(EUCOMM)Hmgu
Tg(Cd4-cre)1Cwi/0  (conditional)
*
Zranb1tm1c(EUCOMM)Hmgu/Zranb1tm1c(EUCOMM)Hmgu
Tg(Itgax-cre)1-1Reiz/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory