|
Symbol Name ID |
Il4ra
interleukin 4 receptor, alpha MGI:105367 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Allergic rhinitis |
Conjunctivitis |
Lymphadenopathy |
Splenomegaly |
Eczematoid dermatitis |
Atopic dermatitis |
Recurrent skin infections |
Anti-citrullinated protein antibody positivity |
Rheumatoid factor positive |
Asthma |
| Disease(s) Associated with IL4R | ||||||||||||||
| asthma | ||||||||||||||
| atopic dermatitis | ||||||||||||||
| multiple myeloma | ||||||||||||||
| rheumatoid arthritis |
| Mouse Phenotypes | impaired macrophage chemotaxis |
decreased T cell proliferation |
increased eosinophil cell number |
decreased T-helper 2 cell number |
increased monocyte cell number |
abnormal T-helper 2 cell morphology |
abnormal microglial cell morphology |
decreased IgE level |
increased IgE level |
decreased IgG1 level |
increased IgG2a level |
increased IgG level |
abnormal T-helper 2 physiology |
abnormal macrophage physiology |
abnormal macrophage activation involved in immune response |
abnormal circulating cytokine level |
abnormal circulating interferon-gamma level |
increased circulating interleukin-4 level |
abnormal immune system physiology |
increased susceptibility to type I hypersensitivity reaction |
abnormal immune serum protein physiology |
abnormal cytokine secretion |
decreased interleukin-10 secretion |
decreased interleukin-4 secretion |
increased interleukin-4 secretion |
decreased interleukin-5 secretion |
granulomatous inflammation |
liver inflammation |
respiratory system inflammation |
abnormal susceptibility to infection |
decreased susceptibility to parasitic infection |
increased susceptibility to parasitic infection |
increased susceptibility to infection |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||
| Il4raM1Btlr/Il4raM1Btlr | ||||||||||||||||||||||||||||||||||
| Il4raM2Btlr/Il4raM2Btlr | ||||||||||||||||||||||||||||||||||
| Il4ratm1Fbb/Il4ratm1Fbb | ||||||||||||||||||||||||||||||||||
| Il4ratm1Sz/Il4ratm1Sz | ||||||||||||||||||||||||||||||||||
| Il4ratm1Tch/Il4ratm1Tch | ||||||||||||||||||||||||||||||||||
| Il4ratm2Tch/Il4ratm2Tch | ||||||||||||||||||||||||||||||||||
| Il4ratm3.1Tch/Il4ratm3.1Tch | ||||||||||||||||||||||||||||||||||
| Il4ratm1Fbb/Il4ratm2Fbb Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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