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Symbol
Name
ID

Ptx3
pentraxin related gene
MGI:104641

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes

Sinusitis

Chronic sinusitis

Hepatosplenomegaly

Pancreatitis

Recurrent pneumonia

Asthma

Nontuberculous mycobacterial pulmonary infection

Recurrent Burkholderia cepacia infections

Recurrent Haemophilus influenzae infections

Recurrent Staphylococcus aureus infections

Recurrent Aspergillus infections

Recurrent respiratory infections

Recurrent bronchopulmonary infections

Recurrent lower respiratory tract infections

Disease(s) Associated with PTX3

cystic fibrosis

Mouse Phenotypes		impaired macrophage phagocytosis	abnormal T-helper 1 physiology	abnormal macrophage physiology	abnormal professional antigen presenting cell physiology	abnormal dendritic cell physiology	lung inflammation	increased susceptibility to bacterial infection	increased susceptibility to fungal infection	increased susceptibility to Coronaviridae infection
Availability	Mouse Genotype	impaired macrophage phagocytosis	abnormal T-helper 1 physiology	abnormal macrophage physiology	abnormal professional antigen presenting cell physiology	abnormal dendritic cell physiology	lung inflammation	increased susceptibility to bacterial infection	increased susceptibility to fungal infection	increased susceptibility to Coronaviridae infection
	Ptx3^tm1Mant/Ptx3^tm1Mant
	Ptx3^tm1Zuk/Ptx3^tm1Zuk

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23