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Symbol Name ID |
Arhgef2
Rho/Rac guanine nucleotide exchange factor 2 MGI:103264 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Skin rash |
| Disease(s) Associated with ARHGEF2 | |
| neurodevelopmental disorder with midbrain and hindbrain malformations |
| Mouse Phenotypes | immune system phenotype |
abnormal spleen morphology |
small spleen |
abnormal macrophage physiology |
decreased interferon-beta secretion |
increased susceptibility to Orthomyxoviridae infection |
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| Availability | Mouse Genotype | ||||||
| Arhgef2em1(IMPC)Mbp/Arhgef2em1(IMPC)Mbp | |||||||
| Arhgef2Gt(IST13976A8)Tigm/Arhgef2Gt(IST13976A8)Tigm | * | ||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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