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Symbol
Name
ID
Mfge8
milk fat globule EGF and factor V/VIII domain containing
MGI:102768
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Recurrent pharyngitis
Pericarditis
Mediastinal lymphadenopathy
Meningitis
Disease(s) Associated with MFGE8
temporal arteritis

Mouse Phenotypes
immune system phenotype
impaired macrophage phagocytosis
mastitis
enlarged spleen
increased spleen weight
spleen hyperplasia
abnormal spleen morphology
increased spleen B cell follicle size
increased spleen white pulp amount
increased anti-double stranded DNA antibody level
spermatic granuloma
Availability Mouse Genotype
Mfge8Gt(KST227)Byg/Mfge8Gt(KST227)Byg
Mfge8tm1Mcu/Mfge8tm1Mcu
Mfge8tm1Osa/Mfge8tm1Osa *!
Mfge8tm1Shur/Mfge8tm1Shur

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory