|
Symbol Name ID |
Runx3
runt related transcription factor 3 MGI:102672 |
| Darker colors indicate more annotations |
| Human Phenotypes | Lymphadenopathy |
Hepatosplenomegaly |
Peritoneal abscess |
| Disease(s) Associated with RUNX3 | |||
| pancreatic cancer |
| Mouse Phenotypes | abnormal dendritic cell differentiation |
intestinal inflammation |
colitis |
small intestinal inflammation |
stomach inflammation |
abnormal CD8-positive, alpha-beta T cell differentiation |
abnormal double-positive T cell morphology |
absent Langerhans cell |
increased dendritic cell number |
decreased CD8-positive, alpha-beta T cell number |
abnormal dendritic cell morphology |
abnormal CD8-positive, alpha beta T cell morphology |
increased IgA level |
increased IgE level |
abnormal cytokine level |
abnormal interferon level |
abnormal interleukin level |
abnormal tumor necrosis factor level |
abnormal mesenteric lymph node morphology |
abnormal immune system physiology |
abnormal dendritic cell physiology |
abnormal inflammatory response |
lung inflammation |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Runx3tm1Litt/Runx3tm1Litt | ||||||||||||||||||||||||
| Runx3tm1Yg/Runx3tm1Yg | ||||||||||||||||||||||||
| Runx3tm2Yg/Runx3tm2Yg | ||||||||||||||||||||||||
| Runx3tm3.1Yg/Runx3tm3.1Yg | ||||||||||||||||||||||||
| Runx3tm1Itan/Runx3tm1Itan Tg(Cd4-cre)1Cwi/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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