Symbol Name ID |
Traf2
TNF receptor-associated factor 2 MGI:101835 |
Darker colors indicate more annotations |
Mouse Phenotypes | increased thymocyte apoptosis |
thymus atrophy |
decreased thymocyte number |
enlarged spleen |
decreased immature B cell number |
decreased double-positive T cell number |
increased granulocyte number |
decreased mature B cell number |
absent follicular B cells |
absent marginal zone B cells |
increased follicular B cell number |
increased marginal zone B cell number |
increased B cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased alpha-beta T cell number |
decreased lymphocyte cell number |
abnormal spleen morphology |
spleen atrophy |
absent spleen germinal center |
abnormal spleen marginal zone morphology |
abnormal B cell physiology |
increased circulating tumor necrosis factor level |
absent lymph node germinal center |
enlarged lymph nodes |
lymph node hyperplasia |
lymphoid hypoplasia |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||
Traf2tm1Mak/Traf2tm1Mak | |||||||||||||||||||||||||||
Traf2tm1a(EUCOMM)Wtsi/Traf2+ | |||||||||||||||||||||||||||
Tg(Mx1-cre)1Cgn/0 Traf2tm1Rbr/Traf2tm1Rbr (conditional) |
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Cd19tm1(cre)Cgn/Cd19+ Traf2tm1Rbr/Traf2tm1Rbr (conditional) |
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Tg(Lck-cre)I57Jxm/? Traf2tm1Rbr/Traf2tm1Rbr (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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