Symbol Name ID |
Aldh2
aldehyde dehydrogenase 2, mitochondrial MGI:99600 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased level of 1,5 anhydroglucitol in serum |
Elevated circulating hepatic transaminase concentration |
Hyperglycemia |
Diabetes mellitus |
Type II diabetes mellitus |
Insulin resistance |
Ketoacidosis |
Hepatic steatosis |
Disease(s) Associated with ALDH2 | ||||||||
metabolic dysfunction-associated steatotic liver disease | ||||||||
pancreatic cancer | ||||||||
type 1 diabetes mellitus | ||||||||
type 2 diabetes mellitus |
Mouse Phenotypes | impaired exercise endurance |
abnormal circulating hormone level |
decreased circulating HDL cholesterol level |
decreased circulating LDL cholesterol level |
decreased circulating cholesterol level |
increased circulating free fatty acids level |
decreased circulating alkaline phosphatase level |
decreased circulating total protein level |
abnormal enzyme/coenzyme activity |
abnormal ethanol metabolism |
increased incidence of tumors by chemical induction |
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Availability | Mouse Genotype | |||||||||||
Aldh2tm1.1Mak/Aldh2tm1.1Mak | ||||||||||||
Aldh2tm1a(EUCOMM)Wtsi/Aldh2tm1a(EUCOMM)Wtsi | ||||||||||||
Aldh2tm1Kaw/Aldh2tm1Kaw | ||||||||||||
Aldh2tm1.1Mak/Aldh2+ | ||||||||||||
Aldh2tm1Dmro/Aldh2+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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