Symbol Name ID |
Atp7a
ATPase, Cu++ transporting, alpha polypeptide MGI:99400 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased circulating copper concentration |
Decreased circulating ceruloplasmin concentration |
Hypothermia |
Atypical scarring of skin |
Keloids |
Scarring |
Cerebral calcification |
Disease(s) Associated with ATP7A | |||||||
Menkes disease | |||||||
occipital horn syndrome |
Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased creatine level |
decreased circulating copper level |
decreased circulating ceruloplasmin level |
abnormal noradrenaline level |
decreased noradrenaline level |
abnormal ion homeostasis |
abnormal copper homeostasis |
abnormal copper level |
decreased brainstem copper level |
decreased brain copper level |
increased brain copper level |
increased intestine copper level |
increased kidney copper level |
abnormal liver copper level |
decreased liver copper level |
abnormal pH regulation |
abnormal enzyme/coenzyme activity |
decreased creatine kinase activity |
|
Availability | Mouse Genotype | |||||||||||||||||||
Atp7aMo-blo/Atp7a+ | ||||||||||||||||||||
Atp7aMo-brJ/Atp7a+ | * | |||||||||||||||||||
Atp7aMo-dp/Atp7a+ | ||||||||||||||||||||
Atp7aMo-ml/Atp7a+ | ||||||||||||||||||||
Atp7aMo-to/Atp7a+ | ||||||||||||||||||||
Atp7aMo-Tohm/Atp7a+ | ||||||||||||||||||||
Atp7aMo-3Btlr/Y | ||||||||||||||||||||
Atp7aMo-blo/Y | ||||||||||||||||||||
Atp7aMo-br/Y | ||||||||||||||||||||
Atp7aMo-brJ/Y | ||||||||||||||||||||
Atp7aMo-ml/Y | * | |||||||||||||||||||
Atp7aMo-ms/Y | ||||||||||||||||||||
Atp7aMo-Tohm/Y | ||||||||||||||||||||
Atp7aMo-vbr/Y | * | |||||||||||||||||||
Atp7atm1.2Mlke/Y | ||||||||||||||||||||
Atp7aMo-blo/? | ||||||||||||||||||||
Atp7atm1.1Mjp/Y Mnx1tm4(cre)Tmj/Mnx1+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/14/2024 MGI 6.23 |
|
|