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Symbol
Name
ID

Xdh
xanthine dehydrogenase
MGI:98973

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hyperxanthinemia	Hyperuricemia	Hypouricemia	Reduced circulating xanthine oxidase activity	Reduced xanthine dehydrogenase level	Hyperuricosuria	Xanthinuria
Disease(s) Associated with XDH	Hyperxanthinemia	Hyperuricemia	Hypouricemia	Reduced circulating xanthine oxidase activity	Reduced xanthine dehydrogenase level	Hyperuricosuria	Xanthinuria
Lesch-Nyhan syndrome
xanthinuria type I

Mouse Phenotypes

homeostasis/metabolism phenotype

increased circulating creatinine level

increased blood urea nitrogen level

decreased blood uric acid level

increased circulating hypoxanthine level

increased circulating calcium level

increased circulating alkaline phosphatase level

increased circulating amylase level

increased circulating xanthine level

hypoxia

abnormal lipid homeostasis

increased triglyceride level

increased urine hypoxanthine level

increased urine xanthine level

crystalluria

Availability

Mouse Genotype

Xdh^renf/Xdh^renf

Xdh^tm1Fink/Xdh^tm1Fink

*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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