Symbol Name ID |
Notch2
notch 2 MGI:97364 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating hepatic transaminase concentration |
Renal tubular acidosis |
Hematuria |
Proteinuria |
Disease(s) Associated with NOTCH2 | ||||||
Alagille syndrome |
Mouse Phenotypes | homeostasis/metabolism phenotype |
pericardial edema |
pericardial effusion |
increased circulating bilirubin level |
increased circulating interleukin-6 level |
increased circulating alanine transaminase level |
increased circulating alkaline phosphatase level |
increased circulating type I collagen C-terminal telopeptide level |
cyanosis |
skin edema |
abnormal interleukin level |
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Availability | Mouse Genotype | |||||||||||
Notch2tm1Grid/Notch2tm1Grid | ||||||||||||
Notch2tm2Grid/Notch2tm2Grid | ||||||||||||
Notch2tm3.1Grid/Notch2tm3.1Grid | ||||||||||||
Notch2tm1.1Hhtg/Notch2+ | ||||||||||||
Notch2tm2Grid/Notch2tm3Grid Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
* | |||||||||||
Notch2tm3Grid/Notch2tm3.1Grid Tg(Tagln-cre)1Her/? (conditional) |
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Notch2tm3Grid/Notch2tm3.1Grid Pax3tm1(cre)Joe/Pax3+ (conditional) |
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Notch2tm3Grid/Notch2tm3.1Grid Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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