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Symbol Name ID |
Ddc
dopa decarboxylase MGI:94876 |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased CSF homovanillic acid concentration |
Decreased CSF 5-hydroxyindolacetic acid concentration |
Reduced circulating aromatic L-amino acid decarboxylase activity |
Hypoglycemia |
Intermittent hypothermia |
Temperature instability |
| Disease(s) Associated with DDC | ||||||
| aromatic L-amino acid decarboxylase deficiency |
| Mouse Phenotypes | impaired adaptive thermogenesis |
increased circulating creatinine level |
decreased circulating aldosterone level |
abnormal dopamine level |
decreased dopamine level |
abnormal noradrenaline level |
decreased serotonin level |
albuminuria |
decreased renin activity |
increased renin activity |
abnormal response/metabolism to endogenous compounds |
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| Availability | Mouse Genotype | |||||||||||
| Ddctm1.1Nwlh/Ddctm1.1Nwlh | ||||||||||||
| Ddctm1Umon/Ddctm1Umon | ||||||||||||
| Ddctm1.1Rhrs/Ddctm1.1Rhrs Tg(Ggt1-cre)M3Egn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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