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Symbol
Name
ID
Apoa1
apolipoprotein A-I
MGI:88049
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Decreased HDL cholesterol concentration
Increased LDL cholesterol concentration
Fever
Hematuria
Pyuria
Proteinuria
Disease(s) Associated with APOA1
familial hypercholesterolemia
primary hypoalphalipoproteinemia 2
systemic lupus erythematosus

Mouse Phenotypes
abnormal vascular wound healing
abnormal cellular cholesterol metabolism
decreased cholesterol efflux
decreased circulating HDL cholesterol level
decreased circulating LDL cholesterol level
decreased circulating VLDL cholesterol level
decreased circulating cholesterol level
increased circulating cholesterol level
decreased circulating phospholipid level
increased circulating triglyceride level
Availability Mouse Genotype
Apoa1tm1Bres/Apoa1tm1Bres
Apoa1tm1Unc/Apoa1tm1Unc
Apoa1tm1Bres/Apoa1+
Apoa1tm1Unc/Apoa1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory