Symbol Name ID |
Apc
APC, WNT signaling pathway regulator MGI:88039 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Elevated circulating hepatic transaminase concentration |
Diabetes mellitus |
Increased level of L-fucose in urine |
Keloids |
Cerebellar calcifications |
Disease(s) Associated with APC | |||||
familial adenomatous polyposis 1 | |||||
medulloblastoma | |||||
pancreatic cancer | |||||
stomach cancer |
Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal autophagy |
increased blood urea nitrogen level |
increased circulating cholesterol level |
increased circulating free fatty acids level |
increased circulating triglyceride level |
hyperlipidemia |
increased circulating tumor necrosis factor level |
increased prostaglandin level |
increased incidence of tumors by chemical induction |
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Availability | Mouse Genotype | ||||||||||
Apctm1Tno/Apctm1Tno | |||||||||||
ApcMin/Apc+ | |||||||||||
Apctm2Tno/Apc+ | |||||||||||
Apctm1Kk/Apctm1Kk Tg(Lck-cre)1Cwi/? (conditional) |
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Apctm1Tno/Apctm1Tno Tg(Cdh16-cre)91Igr/0 (conditional) |
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Apctm2.1Cip/Apc+ Tg(Vil1-cre/ERT2)23Syr/0 (conditional) |
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Apctm2Rak/Apc+ Tg(Car1-cre)5Flt/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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