Symbol
Name
ID

Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
MGI:2444934

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased resting energy expenditure
Disease(s) Associated with PPARGC1B	Decreased resting energy expenditure
obesity

Mouse Phenotypes

homeostasis/metabolism phenotype

impaired exercise endurance

impaired adaptive thermogenesis

decreased circulating cholesterol level

decreased circulating free fatty acids level

increased circulating free fatty acids level

decreased circulating triglyceride level

increased circulating triglyceride level

decreased oxygen consumption

insulin resistance

increased liver triglyceride level

decreased triglyceride level

abnormal metabolism

enhanced exercise endurance

Availability

Mouse Genotype

Ppargc1b^tm1.1Avp/Ppargc1b^tm1.1Avp

Ppargc1b^tm1.1Dpk/Ppargc1b^tm1.1Dpk

Ppargc1b^tm1.1Rev/Ppargc1b^tm1.1Rev

Ppargc1b^tm1Lowl/Ppargc1b^tm1Lowl

Tg(Ckm-Ppargc1b)T37Brsp/0

Ppargc1b^tm1.1Javi/Ppargc1b^tm1.1Javi
Tg(Fabp4-cre)1Rev/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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