Symbol Name ID |
Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8 MGI:2147834 |
Darker colors indicate more annotations |
Human Phenotypes | Elevated circulating creatine concentration |
Elevated urinary creatine/creatinine ratio |
Disease(s) Associated with SLC6A8 | ||
cerebral creatine deficiency syndrome 1 |
Mouse Phenotypes | decreased aerobic running capacity |
decreased circulating creatine level |
decreased urine creatine level |
increased urine creatine level |
decreased creatine level |
decreased fasting circulating glucose level |
decreased circulating glucose level |
improved glucose tolerance |
increased serotonin level |
abnormal ion homeostasis |
abnormal enzyme/coenzyme activity |
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Availability | Mouse Genotype | |||||||||||
Slc6a8tm1.2Clar/Y | ||||||||||||
Slc6a8tm1.2Lbar/Y | ||||||||||||
Slc6a8tm1e(KOMP)Wtsi/Y | ||||||||||||
Slc6a8tm1.1Clar/Y Tg(Camk2a-cre)2Gsc/0 (conditional) |
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Slc6a8tm1.1Lbar/Y Tg(Nes-cre)1Kln/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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