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Symbol
Name
ID
Mgme1
mitochondrial genome maintenance exonuclease 1
MGI:1921778
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Decreased mitochondrial number
Decreased activity of mitochondrial complex I
Decreased activity of mitochondrial complex IV
Elevated circulating creatine kinase concentration
Exercise intolerance
Disease(s) Associated with MGME1
mitochondrial DNA depletion syndrome 11

Mouse Phenotypes
increased fasting circulating glucose level
improved glucose tolerance
Availability Mouse Genotype
Mgme1em1(IMPC)J/Mgme1em1(IMPC)J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory